Histamine, an organic compound, is involved in many types of allergic and inflammatory processes and helps regulate gut function. Diamine Oxidase (DAO) is the body’s primary enzyme for breaking down histamine and a natural defense against histamine excess. 


Histamine excess may be a result of its release from storage in the body, insufficient breakdown due to a DAO deficiency, or due to the intake of foods rich in histamine-creating substances, such as alcohol, chocolate, pickled foods, as well as certain fish and seafood. Testing histamine and DAO levels provides important information that standard food sensitivity tests may not reveal.

Gut Inflammation: Diamine Oxidase/Histamine